Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1799328-86-1
Chemical Name: Tolinapant; 1-[6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-2H-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2R,5R)-5-methyl-2-[[(3R)-3-methylmorpholin-4-yl]methyl]piperazin-1-yl]ethanone
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel non-peptidomimetic antagonist of cIAP1/2 and XIAP, potently inducing TNF-α dependent apoptosis in cancer cell lines and inhibits tumor growth.
References:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6959437/
https://clincancerres.aacrjournals.org/content/26/12/2819.long
https://www.nature.com/articles/s41418-019-0465-8
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