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MG-277

 

CAS: 2411085-89-5

 

Chemical Name: (3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-N-(5-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)pentyl)-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamide

 

 
GLXC-22130For Lab R&D Uses Only
        Cat No: GLXC-22130

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent inhibitor of the p53-MDM2 interaction with an IC50 value of 67.5 nmol/L, against acute leukemia cell lines with different p53 status and was much less effective in inducing MDM2 degradation

 

Ref: https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.9b00846

 

Analytical data click for PDF file

 

 

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