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CAS: 124-87-8
Chemical Name: Cocculin; (1aR,2aR,3R,6S,6aS,8aS,9R)-2a-Hydroxy-2a1-methyl-9-(prop-1-en-2-yl)hexahydro-8H-1,5,7-trioxa-3,6-methanocyclopenta[ij]cyclopropa[a]azulene-4,8(2a1H)-dione & (1aR,2aR,3R,6S,6aS,8aS,9S)-2a-hydroxy-9-(2-hydroxypropan-2-yl)-2a1-methylhexahydro-8H-1,5,7-trioxa-3,6-methanocyclopenta[ij]cyclopropa[a]azulene-4,8(2a1H)-dione
Purity: >98% (HPLC)
Noncompetitive antagonist at GABA-A receptors, blocking the GABA-activated chloride ionophore, being used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates
References:
https://pubmed.ncbi.nlm.nih.gov/?cmd=search&term=%22Picrotoxin%22%5BMesh+Terms%3Anoexp%5D
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