Glixx Laboratories Inc

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UNC10112785

 

CAS: 748142-06-5

 

Chemical Name: N-(4-Isopropylphenyl)-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine

 

 
GLXC-21366For Lab R&D Uses Only
        Cat No: GLXC-21366

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent inhibitor of CDK8, CDK19, and CDK9 with IC50 at 1.05, 2.67, and 19.9 nM, respectively, causing MYC loss through both transcriptional and posttranslational mechanisms, and suppressing PDAC anchorage-dependent and anchorage-independent growth, inducing the substantial loss of MYC protein in both two-dimensional (2D) and 3D cell cultures

 

Ref: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728149/

 

Analytical data click for PDF file

 

 

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