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YKL-5-124

 

CAS: 1957203-01-8

 

Chemical Name: YKL-05-124; (S)-3-(4-Acrylamidobenzamido)-N-(2-(dimethylamino)-1-phenylethyl)-6,6-dimethyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxamide

 

 
GLXC-20908For Lab R&D Uses Only
        Cat No: GLXC-20908

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent and highly selective covalent CDK7 inhibitor, causing arrest at the G1/S transition and inhibition of E2F-driven gene expression, resulting in no change to RNA polymerase II C-terminal domain phosphorylation

 

References:

1) https://stke.sciencemag.org/content/13/618/eabb1864

2) https://www.sciencedirect.com/science/article/abs/pii/S2451945619300674

 

Analytical data click for PDF file

 

 

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