Glixx Laboratories Inc
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Chemical Name: (Z)-2-(((1-(Hydroxymethyl)cyclobutyl)methyl)amino)-5-((2-(2-hydroxyphenyl)thiazol-4-yl)methylene)thiazol-4(5H)-one
Purity: >98% (HPLC)
Novel potent pan-PIM inhibitor (15 nM for PIM1), inhibiting proliferation of two PIM-expressing leukaemic cancer cell lines, MV4-11 and K562, and to reduce intracellular phosphorylation of a PIM substrate in a concentration dependent manner
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