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CAS: N/A
Chemical Name: N-(3-(2-Amino-5-methylpyrimidin-4-yl)propyl)-4'-(N-(1-(cyclopropanecarbonyl)-1,2,3,4-tetrahydroquinolin-7-yl)sulfamoyl)-[1,1'-biphenyl]-3-carboxamide
Purity: >98% (HPLC)
Novel dual Inhibitor of repair enzymes 8-oxoguanine DNA glycosylase (OGG1) and human MutT Homolog 1 (NUDT1 or MTH1), increasing sensitivity of tumor cells to oxidative stress
References:
1) https://www.sciencedirect.com/science/article/pii/S2213231720310533
2) https://pubs.acs.org/doi/10.1021/acschembio.0c00877
3) https://pubs.acs.org/doi/10.1021/acschembio.9b00490
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