Glixx Laboratories Inc
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Chemical Name: (E)-4-(Dimethylamino)-N-(4-((3S,4S)-3-methyl-4-((4-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)pyrimidin-2-yl)amino)pyrrolidine-1-carbonyl)phenyl)but-2-enamide
Purity: >98% (HPLC)
Novel selective covalent JNK2 inhibitor, displaying selectivity for JNK2 over JNK1, forming a covalent bond with Cys116 of JNK2, exhibiting a 20-fold higher Kinact/KI compared to that of JNK1, and engaging JNK2 in cells
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