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Glixx Laboratorie
CAS: 90566-53-3
Chemical Name: S-(Fluoromethyl) (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carbothioate
Purity: >98% (HPLC)
Glucocorticoid receptor agonist, resulting in the activation of lipocortin, inhibiting cytosolic phospholipase A2, inducing mitogen-activated protein kinase (MAPK) phosphatase 1, leading to dephosphorylation and inactivation of Jun N-terminal kinase, blocking NFkappaB transcriptional activity.
References:
https://pubmed.ncbi.nlm.nih.gov/?term=Fluticasone&sort=date
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