Glixx Laboratories Inc

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BI-2852

 

CAS: 2375482-51-0

 

Chemical Name: (S)-5-Hydroxy-3-(2-((((1-((1-methyl-1H-imidazol-4-yl)methyl)-1H-indol-6-yl)methyl)amino)methyl)-1H-indol-3-yl)isoindolin-1-one

 

 
GLXC-15818For Lab R&D Uses Only
        Cat No: GLXC-15818

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent inhibitor for GTP-bound KRAS, binding to KRASG12D, inhibiting GTP-KRASG12D binding to effectors like SOS1, CRAF and PI3Kα, showing pERK(2h) modulation and antiproliferative effects in KRASmut cells (NCI-H358)

 

References:

https://pubmed.ncbi.nlm.nih.gov/?term=BI-2852&sort=date

 

Analytical data click for PDF file

 

 

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