Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2171386-10-8
Chemical Name: 2-(4,6-Difluoro-1-(2-hydroxyethyl)spiro[indoline-3,4'-piperidin]-1'-yl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one
Purity: >98% (HPLC)
Novel potent and selective tankyrase inhibitor, potently targeting both tankyrase-1 and tankyrase-2 with no no activity on PARP-1, inhibiting WNT-responsive TCF reporter activity and proliferation of human colorectal cancer cell line COLO-320DM
References:
1) https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00045
2) https://onlinelibrary.wiley.com/doi/full/10.1111/cas.13805
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