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CAS: 2377734-91-1
Chemical Name: Cyclo[N(Me)Ala-D-OAbu(CN)-Ala(CF3)-N(Me)Leu-Ala(CF3)-N(Me)Trp(Bn(4-Br))-Leu]
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel client-selective Sec61 inhibitor with in vivo efficacy, targeting the Sec61 translocon and selectively disrupting secretory and membrane protein biogenesis in a signal peptide-dependent manner
Reference:
https://www.nature.com/articles/s41589-023-01326-1
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