Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2453183-75-8
Chemical Name: (E)-3-(Pyridin-3-yl)-N-(4-(((1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-yl)methyl)amino)phenethyl)acrylamide
Purity: >98% (HPLC)
First-in-class dual inhibitor of NQO1 and NAMPT, selectively inhibiting the proliferation of NQO1-overexpressing A549 cells and taxol-resistant A549/taxol cells and also inducing cell apoptosis and inhibiting cell migration in an NQO1- and NAMPT-dependent manner in A549/taxol cells
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00077
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