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NQO1/NAMPT inhibitor 10d

 

CAS: 2453183-75-8

 

Chemical Name: (E)-3-(Pyridin-3-yl)-N-(4-(((1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-yl)methyl)amino)phenethyl)acrylamide

 

 
GLXC-25839For Lab R&D Uses Only
        Cat No: GLXC-25839

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

First-in-class dual inhibitor of NQO1 and NAMPT, selectively inhibiting the proliferation of NQO1-overexpressing A549 cells and taxol-resistant A549/taxol cells and also inducing cell apoptosis and inhibiting cell migration in an NQO1- and NAMPT-dependent manner in A549/taxol cells

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00077

 

Analytical data click for PDF file

 

 

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