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SOS1 Inhibitor 13c

 

CAS: 2793405-20-4

 

Chemical Name: 1-((S)-12-(((R)-1-(3-(Difluoromethyl)-2-fluorophenyl)ethyl)amino)-10-methyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1',2':4,5][1,4]oxazepino[3,2-g]quinazoline-3-carbonyl)cyclopropane-1-carbonitrile

 

 
GLXC-26336For Lab R&D Uses Only
        Cat No: GLXC-26336

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent orally bioavailable SOS1 inhibitor, strongly disrupting the protein-protein interaction between SOS1 and KRAS with low IC50 values of 3.9 nM (biochemical) and 21 nM (cellular)

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00986

 

Analytical data click for PDF file

 

 

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