Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2928480-72-0
Chemical Name: 3-(3-(N-(((1R,2R,3S,4R)-4-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,3-dihydroxycyclopentyl)methyl)acetamido)prop-1-yn-1-yl)benzamide
Purity: >98% (HPLC)
The first cell-potent NNMT bisubstrate inhibitor, demonstrating a Ki of 5.9 nM in a biochemical assay and a cellular IC50 value of 1.9 μM
References:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00632
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983580/
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