Glixx Laboratories Inc

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Glixx Laboratorie

 

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PQM-181

 

CAS: N/A

 

Chemical Name: (E)-N'-(2-Hydroxybenzylidene)-4-((4-(hydroxymethyl)piperidin-1-yl)methyl)benzohydrazide

 

 
GLXC-26297For Lab R&D Uses Only
        Cat No: GLXC-26297

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel multifunctional anti-Alzheimer agent, showing the best balanced selective and non-competitive inhibition of AChE (IC50 = 5.9 μM, SI > 5.1), with an additional antioxidant activity (IC50 = 7.45 µM) against neuronal t-BOOH-induced oxidative stress and neuroprotective ability against neurotoxicity elicited by both t-BOOH and OAβ1-42, and a moderate ability to interfere in Aβ1-42 aggregates, with low cytotoxicity and good predictive druggability properties

 

Ref: https://www.sciencedirect.com/science/article/abs/pii/S0968089622003455


Analytical data click for PDF file

 

 

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