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LXRß Agonist B9

 

CAS: N/A

 

Chemical Name: tert-Butyl (2'R,3R)-2'-(5-fluoro-4'-(methoxycarbonyl)-3'-(methylsulfonyl)-[1,1'-biphenyl]-3-yl)-2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

 

 
GLXC-26647For Lab R&D Uses Only
        Cat No: GLXC-26647

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent LXRβ agonist, significantly inhibiting RANKL-induced osteoclast differentiation and bone resorption in vitro and in vivo, selectively activating LXRβ to promote intracellular cholesterol exclusion in osteoclasts and reducing extracellular cholesterol uptake and thereby inhibited osteoclast production

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01661

 

Analytical data click for PDF file

 

 

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