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Glixx Laboratorie
CAS: N/A
Chemical Name: N-(4-((10H-Benzo[b]pyrido[2,3-e][1,4]oxazin-4-yl)oxy)-3-fluorophenyl)-5-(4-fluorophenyl)-1-isopropyl-4-oxo-1,4-dihydropyridine-3-carboxamide
Purity: >98% (HPLC)
Novel potent and orally bioavailable AXL inhibitor, displaying about 15-fold selectivity for AXL over its highly homologous kinase c-Met, exhibiting significant antitumor efficacy in AXL-driven xenograft
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00962
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