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 ARV-771

 

CAS: 1949837-12-0

 

Chemical Name: (2S,4R)-1-[(2S)-2-{2-[3-(2-{2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0 (2, 6)]trideca-2(6),4,7,10,12-pentaen-9-yl]acetamido}ethoxy)propoxy]acetamido}-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide

 

 

GLXC-08850        Cat No: GLXC-08850

 

 

Purity:               > 98% (HPLC)

Storage:             Refrigerator (4 °C)

 


Product Description:

pan-BET degrader, demonstrating dramatically improved efficacy in cellular models of CRPC as compared with BET inhibition. Unlike BET inhibitors, ARV-771 results in suppression of both AR signaling and AR levels and leads to tumor regression in a CRPC mouse xenograft model

 

Analytical data click for PDF file

 

 

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