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Glixx Laboratories
CAS: 186139-09-3
Chemical Name: MSI-1436; Aminosterol-1436; [(3R,6R)-6-[(3S,5R,7R,8R,9S,10S,13R,14S,17R)-3-[3-[4-(3-Aminopropylamino)butylamino]propylamino]-7-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] hydrogen sulfate
Cat No: GLXC-11140
Purity: >98% (HPLC)
Storage: Refrigerator (4 °C)
Naturally-occurring cholestane and non-competitive, allosteric inhibitor of protein tyrosine phosphatase 1B (PTP1B), with potential hypoglycemic, anti-diabetic, anti-obesity, and antineoplastic activities
References:
1) https://pubs.acs.org/doi/10.1021/acschembio.8b00466
2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062594/
3) https://www.nature.com/articles/s41467-018-07699-5
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