Glixx Laboratories Inc
Your exclusive source for bioactive molecules
Chemical Name: 1-Methyl-7-(3-(trifluoromethyl)-1H-pyrazol-4-yl)-8,9,10,11-tetrahydro-3H-pyrazolo[4,3-a]phenanthridine
Purity: >98% (HPLC)
Novel potent inhibitor of the recombinant FLT3 kinase and its mutant forms, blocking the proliferation of AML cell lines, harboring oncogenic FLT3-ITD mutations with remarkable IC50 values, which were comparable to the approved FLT3 inhibitor quizartinib, also inhibiting the growth of leukemia in a mouse-disseminated AML model
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