Glixx Laboratories Inc

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Glixx Laboratorie

 

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HSD1237

 

CAS: N/A

 

Chemical Name: 1-Methyl-7-(3-(trifluoromethyl)-1H-pyrazol-4-yl)-8,9,10,11-tetrahydro-3H-pyrazolo[4,3-a]phenanthridine

 

 
GLXC-24321For Lab R&D Uses Only
        Cat No: GLXC-24321

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel potent inhibitor of the recombinant FLT3 kinase and its mutant forms, blocking the proliferation of AML cell lines, harboring oncogenic FLT3-ITD mutations with remarkable IC50 values, which were comparable to the approved FLT3 inhibitor quizartinib, also inhibiting the growth of leukemia in a mouse-disseminated AML model

 

Ref: https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.1c00330

 

Analytical data click for PDF file

 

 

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