Glixx Laboratories Inc
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Chemical Name: (11aS,11a'S)-8,8'-(Pentane-1,5-diylbis(oxy))bis(7-methoxy-2-methyl-1,11a-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one)
Purity: >98% (HPLC)
Novel PBD dimer, binding in the minor groove of DNA, forming covalent DNA interstrand cross-links in naked linear plasmid DNA, being potently cytotoxic against a panel of human solid tumour and haematological cancer cell lines
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