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BRAF PROTAC P4B

 

CAS: N/A

 

Chemical Name: N-(3-(5-((4-(1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oyl)cyclohexyl)(methyl)amino)-3-(pyrimidin-5-yl)-1H-pyrrolo[3,2-b]pyridin-1-yl)-2,4-difluorophenyl)propane-1-sulfonamide

 

 
GLXC-22855For Lab R&D Uses Only
        Cat No: GLXC-22855

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

PROTAC directed against BRAF mutant V600E, displaying superior specificity and inhibitory properties relative to non-PROTAC controls in BRAF(V600E) cell lines, harboring alternative BRAF mutations that impart resistance to conventional BRAF inhibitors

 

Ref: https://www.nature.com/articles/s41589-020-0609-7

 

Analytical data click for PDF file

 

 

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