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CAS: N/A
Chemical Name: (2S,4R)-1-((S)-2-(2-(4-(2-(2-((2R,6S)-4-(4-((5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)carbamoyl)phenyl)-2,6-dimethylpiperazin-1-yl)acetamido)ethyl)phenoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide
Purity: >98% (HPLC)
Novel potent and selective FGFR1 degrader, inhibiting the proliferation of FGFR1 amplification DMS114 and NCI-H1581 cells with IC50s of 139 and 160 nM, respectively
Ref: https://www.sciencedirect.com/science/article/abs/pii/S0960894X22004589
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