Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2097132-94-8
Chemical Name: BLU667; (1s,4R)-N-((S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethyl)-1-methoxy-4-(4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)cyclohexane-1-carboxamide
Purity: >98% (HPLC)
Novel highly potent and selective inhibitor of oncogenic RET fusion, inhibiting Wt RET, RET mutants V804L, V804M, M918T, and CCDC6-RET fusion, displaying broad and robust anti-tumor activity against multiple RET-driven solid tumor types
References:
https://pubmed.ncbi.nlm.nih.gov/?term=Pralsetinib+&sort=date
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