Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1395347-24-6
Chemical Name: (5S,10aS)-5-(5-Chloro-1H-indol-3-yl)-9-methyl-8,9,10a,11-tetrahydro-5H-[1,3]dioxolo[4,5-g]pyrazino[1,2-b]isoquinoline-7,10-dione
Purity: >98% (HPLC)
Novel PIP5K1α inhibitor, disrupting protein stabilization of AR-V7 which is dependent on PIP5K1α, leading to suppression of invasive growth of AR-V7-high tumors in xenograft mice
References:
1) https://febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12873
2) https://www.mdpi.com/2072-6694/12/9/2719
3) https://www.nature.com/articles/s41388-018-0438-2
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