Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2248691-29-2
Chemical Name: N1,N1-dimethyl-N3-(6-phenyl-2-(piperidin-4-yl)pyrimidin-4-yl)benzene-1,3-diamine
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel blocker of the interaction of CDC42 GTPases with specific downstream effectors, blocking tumor growth in BRAF mutant mouse melanoma models and patient-derived xenografts (PDXs) in vivo, also inhibiting tumor angiogenesis in three-dimensional vascularized microtumor models in vitro
References:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c0
https://www.cell.com/cell-reports/fulltext/S2211-1247(22)00393-X
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