Glixx Laboratories Inc

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ARN22089

 

CAS: 2248691-29-2

 

Chemical Name: N1,N1-dimethyl-N3-(6-phenyl-2-(piperidin-4-yl)pyrimidin-4-yl)benzene-1,3-diamine

 

 
GLXC-27206For Lab R&D Uses Only
        Cat No: GLXC-27206

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel blocker of the interaction of CDC42 GTPases with specific downstream effectors, blocking tumor growth in BRAF mutant mouse melanoma models and patient-derived xenografts (PDXs) in vivo, also inhibiting tumor angiogenesis in three-dimensional vascularized microtumor models in vitro

 

References:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c0

 

https://www.cell.com/cell-reports/fulltext/S2211-1247(22)00393-X


Analytical data click for PDF file

 

 

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