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CAS: N/A
Chemical Name: 4-(1-(2-chloro-6-(trifluoromethyl)benzoyl)-6-(((R)-52-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-49-oxo-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxa-48-azatripentacontyl)carbamoyl)-1H-indazol-3-yl)benzoic acid
Purity: >98% (HPLC)
Novel potent antagonist of RORγt function, displaying an increased selectivity for RORγt over RORα and PPARγ compared to the purely orthosteric and allosteric non-PEG-linked parent compounds
Ref: https://pubs.acs.org/doi/10.1021/acschembio.0c00941
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