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Glixx Laboratorie
CAS: 1808951-93-0
Chemical Name: 2-Methyl-propane-1-sulfonic acid [2(R)-(4-chloro-phenyl)-1-(1,4-dimethyl-2-oxo-1,2-dihydro-quinolin-7-yl)-6-oxo-piperidin-3(S)-yl]-amide
Cat No: GLXC-06266
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
Novel BRD7/9 specific inhibitor, binding to BRD9 with a higher potency (Kd=99nM) than to BRD7 (Kd=909nM, ITC), with no off-target selectivity in vitro
References:
1) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871321/
2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449114/
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