Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2457232-14-1
Chemical Name: 4-((5-Oxo-6,7,8,9-tetrahydro-5H-cyclohepta[d]pyrimidin-2-yl)amino)thiophene-2-carbonitrile
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel G6PD inhibitor, revealing immune dependence on pentose phosphate pathway. depleting NADPH most strongly in lymphocytes, markedly decreasing inflammatory cytokine production in T calls, suppressing respiratory burst in neutrophils
Ref: https://www.nature.com/articles/s41589-020-0533-x
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