Glixx Laboratories Inc

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PHI1

 

CAS: N/A

 

Chemical Name: 3-(Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-(((2-morpholinoethyl)amino)methyl)-3-(trifluoromethyl)phenyl)benzamide

 

 
GLXC-22835For Lab R&D Uses Only
        Cat No: GLXC-22835

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel BRAF dimer kinase inhibitor, being selective for oncogenic BRAF dimers, showing high inhibitory potency IC50=10nM against BRAFV600E kinase activity, inducing an αC-IN* conformation within the BRAFV600E dimer through interactions within its allosteric site

 

Ref: https://www.nature.com/articles/s41467-020-18123-2

 

Analytical data click for PDF file

 

 

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