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CAS: N/A
Chemical Name: 2-((6-(3,5-Dimethylisoxazol-4-yl)-1-methyl-2-oxo-4-phenyl-1,4-dihydroquinazolin-3(2H)-yl)methyl)-1H-benzo[d]imidazole-4-carboxamide
Purity: >98% (HPLC)
Novel highly selective dual PARP1/BRD4 inhibitor (PARP1 IC50=49nM; BRD4 IC50=202nM), repressing the expression and activity of PARP1 and BRD4 to synergistically inhibit the malignant growth of pancreatic cancer cells in vitro and in vivo
Ref: https://www.sciencedirect.com/science/article/abs/pii/S0223523422000186
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