Glixx Laboratories Inc
Your exclusive source for bioactive molecules
Glixx Laboratorie
CAS: 2360851-29-0
Chemical Name: RBN-012759; 7-(Cyclopropylmethoxy)-5-fluoro-2-((((1r,4r)-4-hydroxycyclohexyl)thio)methyl)quinazolin-4(3H)-one
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel, potent, selective and orally active inhibitor of PARP14 (IC50 of <3 nM), displaying 300-fold selectivity over the monoPARPs and 1000-fold selectivity over the polyPARPs
References:
https://www.cell.com/cell-chemical-biology/fulltext/S2451-9456(21)00095-7
https://ribontx.com/wp-content/uploads/2020/04/L.-SCHENKEL-2020_FINAL.pdf
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