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Glixx Laboratorie
CAS: 2850357-97-8 (free base: 2091918-57-7)
Chemical Name: N-((3aS,4S,9S,10aS)-4-((2,5-dioxopyrrolidin-1-yl)methyl)-10,10-dihydroxy-2,6-diiminooctahydro-1H,8H-pyrrolo[1,2-c]purin-9-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide bis-TFA salt
Purity: >98% (HPLC)
Novel selective NaV1.7 inhibitor, blocking the extracellular vestibule of the channel with an IC50 of 72 nM and greater than 200-fold selectivity over off-target sodium channel isoforms, NaV1.1-1.6 and NaV1.8
Ref: https://www.nature.com/articles/s41598-020-71135-2
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