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CAS: 937820-89-8
Chemical Name: (E)-1-(3-Fluoro-4-methoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one
Purity: >98% (HPLC)
Novel pan-inflammasome inhibitor, inhibiting the secretion of interleukin (IL)-1β and lactate dehydrogenases, and the cleavage of caspase-1 and gasdermin D, blocking the expression of the inflammasome components during the priming step of the inflammasome, and interrupting the production of mitochondrial reactive oxygen species
Reference:
https://www.nature.com/articles/s41598-022-27129-3
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