Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 2369751-07-3
Chemical Name: 1-(6,7-Dichloro-9-(1-methyl-1H-pyrazol-3-yl)-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-2-hydroxyethan-1-one
Purity: >98% (HPLC)
Novel potent cGAS-specific inhibitor for repression of dsDNA-triggered interferon expression ( IC50 of 14 nM and 442 nM for h-cGAS and m-cGAS, respectively)
References:
1) https://onlinelibrary.wiley.com/doi/epdf/10.1111/iej.13636
2) https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00398
3) https://www.nature.com/articles/s41467-019-08620-4
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