Glixx Laboratories Inc

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Glixx Laboratorie

 

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TDI-8414

 

CAS: N /A

 

Chemical Name: (5S,8S,11S)-N-Cyclopentyl-11-(1,1-dioxidoisothiazolidin-2-yl)-8-(2-morpholinoethyl)-7,10-dioxo-2-oxa-6,9-diaza-1,3(1,3)-dibenzenacyclododecaphane-5-carboxamide

 

 
GLXC-26776For Lab R&D Uses Only
        Cat No: GLXC-26776

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel antimalarial Plasmodium proteasome inhibitor, showing nanomolar antiparasitic activity, no toxicity to HepG2 cells, high selectivity against the Plasmodium proteasome over the human constitutive proteasome and immunoproteasome, improved solubility and PAMPA permeability, and enhanced metabolic stability in microsomes and plasma of both humans and mice

 

Reference:

https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01651

 

Analytical data click for PDF file

 

 

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