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CAS: N/A
Chemical Name: {1S-Benzyl-4R-[1-(5-cyclohexyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3(R,S)-ylcarbamoyl)-S-ethylcarbamoyl]-2R-hydroxy-5-phenyl-pentyl}-carbamic acid tert-butyl ester
Purity: >98% (HPLC)
Novel γ-secretase inhibitor, not only physically interacting with presenilin 1 (PS1), but upon chronic treatment producing a “pharmacological knock-down” of PS1 fragments
Ref: http://www.jbc.org/content/276/48/45394.full.pdf
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