Glixx Laboratories Inc

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Glixx Laboratories

 

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ARD-266

 

CAS: N/A

 

Chemical Name: (2S,4R)-N-((S)-3-(4-((4-(((1r,3r)-3-(3-Chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)carbamoyl)phenyl)ethynyl)piperidin-1-yl)-3-oxo-1-phenylpropyl)-4-hydroxy-1-((R)-3-methyl-2-(3-methylisoxazol-5-yl)butanoyl)pyrrolidine-2-carboxamide

 

 
GLXC-21820For Lab R&D Uses Only
        Cat No: GLXC-21820

 

Purity:               >98% (HPLC)

Storage:             Refrigerator (4 °C)

 

 

Product Description:

Novel highly potent proteolysis targeting chimera (PROTAC) AR degrader, effectively inducing degradation of AR protein in AR-positive (AR+) LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC50 values of 0.2-1 nM

 

Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b01393

 

Analytical data click for PDF file

 

 

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