Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1638250-96-0
Chemical Name: ETC-1922159; 2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-purin-7-yl)-N-(6-phenyl-pyridazin-3-yl)-acetamide
Cat No: GLXC-07517
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
Novel inhibitor of PORCN, inhibiting ß-catenin reporter activity in a dose-dependent manner and being highly efficacious in molecularly defined colorectal cancers (CRCs) with R-spondin translocations
References:
1) https://rnajournal.cshlp.org/content/25/12/1696.abstract
2) https://www.nature.com/articles/s41388-019-0908-1
3) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968037/
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