Glixx Laboratories Inc
Your exclusive source for bioactive molecules
Chemical Name: Lazertinib; GNS-1480; N-[5-[[4-[4-[(Dimethylamino)methyl]-3-phenylpyrazol-1-yl]pyrimidin-2-yl]amino]-4-methoxy-2-morpholin-4-ylphenyl]prop-2-enamide
Purity: >98% (HPLC)
Novel irreversible EGFR-TKI with potent intracranial activity in EGFR mutant non-small cell lung cancer, showing more potent inhibition of cancer cell growth compared to osimertinib in cancer cells harboring EGFR mutations (L858R/T790 M) with IC50 of 2 nM vs 8 nM and GI50 of 3.6 nM vs 11.8 nM respectively
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