Glixx Laboratories Inc
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Glixx Laboratorie
CAS: N/A
Chemical Name: 2-(5-(4-Butylphenyl)furan-2-yl)-6-nitroquinoline-4-carboxylic acid
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel RNA-competitive, ATP-uncompetitive eIF4A Inhibitor, decreasing BJAB Burkitt lymphoma cell viability, engaging a novel pocket in the RNA groove of eIF4A and inhibiting unwinding activity by interfering with proper RNA binding and suppressing ATP hydrolysis
Ref: https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c01014
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