Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 179343-17-0
Chemical Name: PD089828; EGF/FGF/PDGF receptor tyrosine kinase inhibitor; 1-[2-amino-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
Cat No: GLXC-06030
Purity: > 98% (HPLC)
Storage: Refrigerator (4 °C)
ATP competitive tyrosine kinase inhibitor, selectively targeting FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively)
References:
1) https://pubs.acs.org/doi/10.1021/jm970367n
2) https://jpet.aspetjournals.org/content/281/3/1446.long
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