Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 888216-25-9
Chemical Name: Ganetespib; STA-9090; 5-(2,4-dihydroxy-5-isopropylphenyl)-4-(1-methyl-1H-indol-5-yl)-2H-1,2,4-triazol-3(4H)-one
Cat No: GLXC-90269
For Lab R&D Uses Only
Purity: >98% (HPLC)
Storage: Refrigerator (4 °C)
The second-generation Hsp90 inhibitor, binding to the ATP-binding domain at the N-terminus of Hsp90 and acting as a potent Hsp90 inhibitor by inducing degradation of multiple oncogenic Hsp90 client proteins including HER2/neu, mutated EGFR, Akt, c-Kit, IGF-1R, PDGFRα, Jak1, Jak2, STAT3, STAT5, HIF-1α, CDC2, c-Met, and Wilms' tumor 1
References:
1) https://pubmed.ncbi.nlm.nih.gov/?term=Ganetespib&sort=date
2) https://pubmed.ncbi.nlm.nih.gov/?term=STA9090&sort=date
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