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CAS: 361198-09-6
Chemical Name: (E)-4-(((Benzo[d][1,3]dioxol-5-ylmethyl)amino)methylene)-2-(benzo[d]thiazol-2-yl)-5-(((4-chlorophenyl)thio)methyl)-2,4-dihydro-3H-pyrazol-3-one
Purity: >98% (HPLC)
Novel activator of SIRT1, inducing autophagic cell death via the AMPK-mTOR-ULK complex and inducing mitophagy by the SIRT1-PINK1-Parkin pathway, downregulating 14-3-3γ, catalase, profilin-1, and HSP90α
Ref: https://www.nature.com/articles/s41419-018-0799-z
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