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CAS: N/A
Chemical Name: (S)-N-Ethyl-2-((1R,3aS,3bS,10aR,10bS,12aS)-6,6,10a,12a-tetramethyl-2,3,3a,3b,4,6,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[2,3-d][1,2,3]thiadiazol-1-yl)propanamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel potent antiosteoporosis agent, displaying 100% inhibition at 1.0 μM and 82.8% inhibition at an even lower concentration of 0.1 μM, inhibiting the expression of osteoclastogenesis-related marker genes and proteins, including TRAP, TRAF6, c-Fos, CTSK, and MMP9
Reference:
https://pubs.acs.org/doi/10.1021/acs.jmedchem.4c00349
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