Glixx Laboratories Inc
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Glixx Laboratorie
CAS: 1257628-77-5
Chemical Name: Olverembatinib; GZD-824; 4-Methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[2-(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]benzamide
For Lab R&D Uses Only
Purity: >98% (HPLC)
Novel orally bioavailable inhibitor against a broad spectrum of Bcr-Abl mutants including T315I. It tightly bound to Bcr-Abl(WT) and Bcr-Abl(T315I)
References:
https://molpharm.aspetjournals.org/content/98/6/669.long
https://www.cell.com/molecular-cell/fulltext/S1097-2765(20)30420-2
https://www.sciencedirect.com/science/article/pii/S1936523319307612
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