For Lab R&D Uses Only

Purity:               >98% (HPLC)

Product Description:

Second-generation sphingosine 1-phosphate (S1P) receptor modulator that exhibits selectivity for S1P receptors 1 and 5, reducing the severity of bone marrow (BM) failure in a dose-dependent manner, resulting in higher blood and BM cell counts, Regulating trafficking of T lymphocytes and hematopoietic stem cells, and alleviatingiImmune-mediated aplastic anemia in a mouse model

References:

1) https://jpet.aspetjournals.org/content/early/2020/11/30/jpet.120.000277.long

2) https://www.nature.com/articles/s41385-018-0077-5

3) https://pubs.acs.org/doi/10.1021/acs.jmedchem.7b00785

Analytical data

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